Table 1 Tumor cell characteristics in tissue sections via THG imaging.

From: Third Harmonic Generation microscopy distinguishes malignant cell grade in human breast tissue biopsies

Grade

MNA ± SEM (μm2)

MCA ± SEM (μm2)

N/C ± SEM

0

82.54 ± 0.67

267.47 ± 0.67

0.254 ± 0.005

I

58.82 ± 0.47

161.38 ± 1.30

0.352 ± 0.003

II

77.35 ± 1.51

186.62 ± 0.62

0.392 ± 0.002

III

64.11 ± 0.52

145.32 ± 1.17

0.443 ± 0.002

  1. N = 150 cells for each grade.
  2. N/C ratio of cancerous tissues (Grade I–III) appear to have statistically significant difference (p < 0.0001****) respectively as compared to Grade 0 tissues.
  3. MNA mean nuclear area, MCA mean cytoplasmic area, N/C ratio mean nuclear to cytoplasmic ratio.
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