Figure 6
From: Association study based on topological constraints of protein–protein interaction networks
Topological differences between the original PIN and null models exemplified by the number of isolated pairs (interactions between k = 1 nodes) in the PIN with observation (red arrow) of 2 isolated pairs. However, the number of isolated pairs in 10,000 null models is distributed from 13 to 289 with a median value of 115 (blue histograms). For comparison also see Fig. 1b,c. The number of isolated pairs in the null models is significantly larger than that in the PIN (p < 1 × 10–4, for 10,000 null models).
