Figure 4 | Scientific Reports

Figure 4

From: Effect of echinalkamide identified from Echinacea purpurea (L.) Moench on the inhibition of osteoclastogenesis and bone resorption

Figure 4The alternative text for this image may have been generated using AI.

Effect of new compounds 13 on the production of NO and TNF-α in LPS-stimulated RAW 264.7 cells. (A) RAW264.7 cells were treated with new compounds 13 or 10 µg/mL LPS for 24 h, after which, cell viability was measured using an MTT assay. Cells were treated new compounds 13 for 1 h before incubation with LPS for 24 h. Culture supernatants were then isolated, and the amounts of (B) NO and (C) TNF-α production were determined. All the data were confirmed by three repeated tests. The results are presented as the mean ± SD. Values with different letters (a, b, c, d, e) are significantly different one from another (one-way ANOVA followed by Newman–Keuls multiple range test, p < 0.05).

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