Table 1 IC50 values.

From: Let-7c regulated epithelial-mesenchymal transition leads to osimertinib resistance in NSCLC cells with EGFR T790M mutations

 

H1975 cells

HCC827-T790M

Control

83.4 ± 1.2

97.2 ± 1.6

 + Pre-Let-7c

64.8 ± 0.9**

82.1 ± 1.8**

 + Anti-Let-7c

147.9 ± 2.0**

171.6 ± 3.4**

  1. All the IC50 values were calculated from the data presented in Fig. 3. Details are provided in the leegend to Fig. 3 and Methods. **p < 0.01, relative to control.