Figure 2
FMR1 mRNA expression among groups and by CGG repeat length. a Box plots showing increased expression levels of FMR1 mRNA in both premutation groups (converters and non-converters) compared to non-carrier healthy controls at V1 (p < 0.001) and V2 (p < 0.001) but no significant differences were observed between the two premutation groups. The heavy line in each box represents the median, the lower and upper box edges represent the 25th and 75th percentiles, respectively, and the lower and upper whiskers represent the smallest and largest observations, respectively. b Scatter plots showing FMR1 mRNA expression as function of CGG repeat number at V1 in the three groups.
