Table 2 Effect of gestational age in the correlation between bilirubin values obtained from AJO-Neo and TSB and the predictive indices of AJO-Neo.

From: Large scale validation of a new non-invasive and non-contact bilirubinometer in neonates with risk factors

Gestational age

Statistical Test

Parameters

Right thumb nail plate

Left thumb nail plate

 < 35 weeks

Linear regression analysis

Regression Coefficient (r)

0.84

0.80

P value

 < 0.0001

 < 0.0001

Slope

0.83

0.77

Intercept

1.52

1.14

Bland altman analysis

Bias (95% CI)

0.55(− 0.09 to 0.21)

0.002(− 0.17 to 0.17)

Standard deviation

1.62

1.83

Limits of agreement

− 3.12 to 3.23

− 3.58 to 3.59

Accuracy

Above 95th percentile

Sensitivity

0.84

0.69

Specificity

0.99

0.99

PPV

0.93

0.89

NPV

0.98

0.98

Above 75th percentile

Sensitivity

0.71

0.57

Specificity

0.97

0.95

PPV

0.83

0.70

NPV

0.94

0.91

Above 40th percentile

Sensitivity

0.88

0.85

Specificity

0.90

0.88

PPV

0.80

0.76

NPV

0.94

0.93

35–38 weeks

Linear regression analysis

Regression Coefficient (r)

0.77

0.74

P value

 < 0.0001

 < 0.0001

Slope

0.64

0.60

Intercept

3.20

3.69

Bland altman analysis

Bias (95% CI)

0.67 (0.56 to 0.79)

0.63 (0.51 to 0.75)

Standard deviation

1.88

1.97

Limits of agreement

− 3.01 to 4.36

− 3.23 to 4.49

Accuracy

Above 95th percentile

Sensitivity

0.52

0.58

Specificity

0.98

0.98

PPV

0.83

0.80

NPV

0.94

0.94

Above 75th percentile

Sensitivity

0.58

0.59

Specificity

0.94

0.94

PPV

0.75

0.75

NPV

0.88

0.88

Above 40th percentile

Sensitivity

0.72

0.71

Specificity

0.90

0.90

PPV

0.86

0.86

NPV

0.79

0.78

 > 38 weeks

Linear Regression Analysis

Regression Coefficient (r)

0.81

0.82

P value

 < 0.0001

 < 0.0001

Slope

0.54

0.52

Intercept

4.24

4.43

Bland altman analysis

Bias (95% CI)

0.50 (− 0.11 to 1.12)

0.50 (− 0.11 to 1.11)

Standard deviation

1.99

1.93

Limits of agreement

− 3.28 to 4.29

− 3.59 to 4.30

Accuracy

Above 95th percentile

Sensitivity

0.83

0.73

Specificity

0.98

0.97

PPV

0.88

0.90

NPV

0.90

0.93

Above 75th percentile

Sensitivity

0.72

0.81

Specificity

0.96

0.96

PPV

0.88

0.90

NPV

0.90

0.83

Above 40th percentile

Sensitivity

0.79

0.79

Specificity

0.98

0.98

PPV

0.98

0.98

NPV

0.72

0.78