Figure 4 | Scientific Reports

Figure 4

From: Combinational therapy with antibiotics and antibiotic-loaded adipose-derived stem cells reduce abscess formation in implant-related infection in rats

Figure 4

μCT imaging analysis of the femur of rats (LaTheta). (A) μCT image of a representative femur of each group; (1) no treatment, (2) ADSCs-ant, (3) antibiotic, (4) ADSCs. (B) Evaluation of the Hounsfield Unit value using the DICOM viewer software (Synapse Vincent). (C) Healthy bone ratio at the proximal screw in all groups. *P < 0.05 versus no treatment and ADSCs; **P < 0.001 versus no treatment and ADSCs; ns, no significant difference by Kruskal–Wallis test followed by Dunn’s post-hoc test. No treatment: mean 0.57, SD 0.07, range 0.47–0.72; ADSCs-ant: mean 0.64, SD 0.05, range 0.52–0.73; antibiotic: mean 0.62, SD 0.06, range 0.53–0.74; ADSCs: mean 0.56, SD 0.06, range 0.46–0.66. (D) Healthy bone ratio at the distal screw in all groups. There were no significant differences between groups by Kruskal–Wallis test followed by Dunn’s post-hoc test.

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