Table 1 Patients and treatment characteristics.

From: Stereotactic irradiation of non-small cell lung cancer brain metastases: evaluation of local and cerebral control in a large series

Characteristics (N = 100)

No. patients

%

Age

 < 60 years

38

38.0%

60–69 years

34

34.0%

 ≥ 70 years

28

28.0%

Sex

Men

77

77.0%

Women

23

23.0%

KPS

90–100

30

30.0%

70–80

58

58.0%

 < 70

12

12.0%

Extra cranial metastasis

42

42%

DS-GPA

0–1

9

9.0%

1.5–2

42

42.0%

2.5–3

41

41.0%

3.5–4

7

7%

RPA

1

28

28.0%

2

59

59.0%

3

12

12.0%

Histology of primitive tumor

Adenocarcinoma

69

69.0%

SCC

23

23.0%

Other

8

8.0%

Number of previous chemotherapy lines (N = 98)

0

47

48.0%

1

32

32.7%

 ≥ 2

19

19.4%

Primary tumor control before SRT (N = 99)

No

22

24.2%

Yes

45

45.5%

Synchronous diagnosis

30

0.3%

Clinical signs

Non symptomatic

54

54%

Symptomatic

44

44.0%

Deficit

26

26.0%

Seizure

13

13.0%

Corticotherapy

41

45.6%

Synchronous or metachronous BM

Synchronous

32

32%

Metachronous

68

68%

No. lesions

1

67

67.0%

2

23

23.0%

 ≥ 3

10

10.0%

Longest diameter (mm) by tumor

Median (range)

14.8

(2–46)

Mean (standard deviation)

16.6

10.4

Tumor localization

Posterior fossa (+ /- other)

23

23%

No posterior fossa

77

77%

Time MRI-treatment (days)

Mean (standard deviation)

27.7

22.5

Time simulation-treatment (days)

Mean (standard deviation)

18.1

12.1

Treatment schedule

27 (Gy)/3 fractions

69

69.0%

18–25 (Gy)/1 fraction

18

18.0%

30 (Gy)/5 fractions

9

9.0%

Other

4

4.0%

  1. KPS Karnofsky performance status, DS-GPA diagnosis-specific graded prognostic assessment, RPA recursive partitioning analysis, SCC squamous cell carcinoma, BM brain metastases, MRI magnetic resonance imaging.