Figure 2

Illustrative examples of LC–MS analysis of degradation products that do not contain formaldehyde reactive amino acids and are derived from formaldehyde- and glycine-treated proteins, as function of cathepsin S digestion time. Error bars represent SD of three enzyme reactions. (A) Kinetics of the cytochrome c peptide MIFA. (B) Kinetics of the cytochrome c peptide EETLM. (C) Kinetics of the cytochrome c peptide GLFG. (D) Kinetics of the β-lactoglobulin A peptide MAASDISLL. (E) Kinetics of the BSA peptide TPTLVE. (F) Kinetics of the BSA peptide APELL.