Figure 7
Non-synonymous gag and vif mutations in the vaccinated macaques. Viral gag and vif cDNAs were amplified from pre-ART and post-ART CD8- cells-derived SIVs obtained at in vitro viral suppression assay and subjected to sequence analyses. Viral gag and vif cDNAs were also amplified from plasma-derived RNAs at weeks 12 and 34 and subjected to sequence analyses. + indicates that the non-synonymous mutation resulting in amino acid substitution was detected predominantly or equivalently with the wild-type sequence. (+) indicates that the wild-type sequence was predominant while the non-synonymous mutation was subdominantly detected.
