Table 1 Macaque experimental protocol.

From: Therapeutic vaccine-mediated Gag-specific CD8+ T-cell induction under anti-retroviral therapy augments anti-virus efficacy of CD8+ cells in simian immunodeficiency virus-infected macaques

Group

Experiment

Macaque

MHC-I haplotype

SIVmac239

iva

ARTb

SeV-Gag/Vif

inc

a-SIV IgG

ivd

N

Exp 1

NE1

E

Wk 0

Wk 12–32

(−)

(−)

N

Exp 1

NE2

E

Wk 0

Wk 12–32

(−)

(−)

N

Exp 2

NE3

E

Wk 0

Wk 12–32

(−)

Wk 32

N

Exp 1

NW4

W

Wk 0

Wk 12–32

(−)

(−)

N

Exp 2

NW5

W

Wk 0

Wk 12–32

(−)

Wk 32

N

Exp 1

NS6

S

Wk 0

Wk 12–32

(−)

(−)

V

Exp 1

VE1

E

Wk 0

Wk 12–32

Wks 26 and 32

Wk 32

V

Exp 1

VE2

E

Wk 0

Wk 12–32

Wks 26 and 32

Wk 32

V

Exp 2

VE3

E

Wk 0

Wk 12–32

Wks 26 and 32

Wk 32

V

Exp 1

VW4

W

Wk 0

Wk 12–32

Wks 26 and 32

Wk 32

V

Exp 2

VW5

W

Wk 0

Wk 12–32

Wks 26 and 32

Wk 32

V

Exp 1

VS6

S

Wk 0

Wk 12–32

Wks 26 and 32

Wk 32

  1. aAnimals were intravenously inoculated with SIVmac239.
  2. bAnimals received ART from week 12 to 32 post-infection.
  3. cAnimals were intranasally immunized with SeV-Gag and SeV-Vif.
  4. dAnimals were intravenously administered with anti-SIV IgG.