Table 5 Evaluation of proteins in DETS through IHC.

From: Structural equation modelling analysis determining causal role among methyltransferases, methylation, and apoptosis during human pregnancy and abortion

Protein(s)

IHC (Fold change ± SEM)

IHC-ROC-URSA-DET

NEP

URSA

p-value

Sensitivity (%)

Specificity (%)

AUC

SE

95% CI

p-value

G9aMT

1.83 ± 0.37

0.40 ± 0.13

 < 0.001

75

60

0.81

0.09

0.612–0.933

0.007

DNMT1

1.83 ± 0.34

0.27 ± 0.12

 < 0.001

83.33

73.33

0.86

0.08

0.674–0.963

0.002

BCL-2

1.58 ± 0.26

0.87 ± 0.13

0.015

50

93.33

0.73

0.10

0.529–0.884

0.040

BAX

0.67 ± 0.19

2.73 ± 0.21

 < 0.001

91.67

93.33

0.94

0.05

0.783–0.996

 < 0.0001

P53

0.75 ± 0.22

2.60 ± 0.22

 < 0.001

83.33

93.33

0.93

0.05

0.763–0.992

0.0001

CASPASE-6

0.42 ± 0.15

2.60 ± 0.21

 < 0.001

93.33

100

0.95

0.05

0.795 to 0.998

 < 0.0001

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