Table 5 Associations between diseases and the five differentially expressed miRNAs extracted from the MNDR database.

From: Circulating miRNAs as molecular markers of occupational grain dust exposure

Disease name

miRNA

hsa-miR-146a-5p

hsa-miR-19b-3p

hsa-miR-574-3p

hsa-miR-124-3p

hsa-miR-18a-5p

CS

Class

CS

Class

CS

Class

CS

Class

CS

Class

Lung cancer

0.4752

W

0.8939

S

0.8939

S

0.8939

S

0.8939

S

Non-small cell lung carcinoma

0.4752

W

0.7606

S

0.7311

S

0.8808

S

0.7606

S

COPD

0.8939

S

0.1097

P

    

0.1097

P

Asthma

0.8589

S

0.1097

P

  

0.1097

P

0.1097

P

Inflammation

0.7311

S

0.1097

P

  

0.1097

P

0.1097

P

Lacunar stroke

0.7311

S

0.4752

W

0.4752

W

0.7311

S

  

Carotid stenosis

        

0.8808

S

Coronary artery disease

0.1097

P

0.9443

S

  

0.1097

P

0.7606

S

Atherosclerosis

0.9526

S

0.5725

W

  

0.1097

P

0.1097

P

Pulmonary hypertension

0.9751

S

        

Intermediate coronary syndrome

0.1097

P

0.8939

S

  

0.1097

P

0.1097

P

Sepsis

0.7311

S

  

0.4752

W

  

0.1097

P

Adenoviridae infections

        

0.7311

S

Nasopharynx carcinoma

      

0.7606

S

  
  1. Confidence score (CS) for miRNA-disease association range from 0.110 to 0.975. Confidence score ranges between 0 and 1; and only well-supported miRNA–disease associations obtain a value close to 1. Class denotes the evidence type for each miRNA-disease association with S representing strong experimental evidence, W representing weak experimental evidence, and P representing prediction evidence; MNDR (Mammalian NcRNA-Disease Repository).
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