Table 1 Demographic and clinical data of the enrolled subjects.

From: Prediction of age at onset in Parkinson’s disease using objective specific neuroimaging genetics based on a sparse canonical correlation analysis

 

All

n = 146

Age at onset, years

p value

Years \(<\) 50

(group1)

n = 24

50 \(\le\) years \(<\) 60

(group2)

n = 35

60 \(\le\) years \(<\) 70

(group3)

n = 54

years \(\ge\) 70

(group4)

n = 33

Age at onset of PD

61.35 \(\pm\) 9.73

46.22 \(\pm\) 3.92

54.82 \(\pm\) 2.90

65.03 \(\pm\) 2.97

73.23 \(\pm\) 2.75

–

Sex, male, % (n)

65.07 (95)

70.83 (17)

45.71 (16)

79.63 (43)

57.58 (19)

–

PD duration, month

7.55 \(\pm\) 6.72

6.25 \(\pm\) 6.75

7.09 \(\pm\) 5.87

8.30 \(\pm\) 0.98

7.79 \(\pm\) 7.22

0.63

H&Y stage

1.68 \(\pm\) 0.54

1.71 \(\pm\) 0.46

1.51 \(\pm\) 0.56

1.67 \(\pm\) 0.55

1.88 \(\pm\) 0.48*

0.04

MDS-UPDRS total

32.32 \(\pm\) 14.97

30.00 \(\pm\) 15.90

32.11 \(\pm\) 12.19

30.59 \(\pm\) 14.99

37.06 \(\pm\) 16.47

0.20

 UPDRS Part1

5.31 \(\pm\) 4.30

4.71 \(\pm\) 4.97

6.00 \(\pm\) 4.78

5.04 \(\pm\) 4.26

5.45 \(\pm\) 3.27

0.66

 UPDRS Part2

5.41 \(\pm\) 3.96

5.88 \(\pm\) 4.97

5.06 \(\pm\) 3.82

5.11 \(\pm\) 3.60

5.94 \(\pm\) 3.97

0.69

 UPDRS Part3

21.45 \(\pm\) 10.20

19.21 \(\pm\) 8.28

\(20.83\pm\) 9.11

20.43 \(\pm\) 9.94

25.42 \(\pm\) 12.16

0.08

 UPDRS Part4

0.15 \(\pm\) 0.72

0.21 \(\pm\) 0.72

0.23 \(\pm\) 0.84

0.02 \(\pm\) 0.14

0.24 \(\pm\) 1.06

0.40

  1. H&Y Hoehn and Yahr, MDS-UPDRS Movement Disorder Society-Unified Parkinson’s Disease Rating Scale.
  2. p value computed from an ANOVA of the four groups.
  3. *p value < 0.05 for comparing group 3 and 4.
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