Figure 5

Histological studies of liver, lungs, and spleen in subject rabbits after H12-ADP-liposome administration following PRP transfusion. (A,D,G) Light micrographs of toluidine blue-stained specimens. (B,E,H) Scanning electron microscopic images of the same parts. (C,F,I) Magnified images of the same parts. Note that elliptical structures representing H12-ADP-liposomes are not bound to platelets and are present in blood vessels. Arrows indicate H12-ADP-liposomes. Double arrows indicate platelets.