Table 1 The characteristics of patients in this cohort.

From: MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia

 

N

%

Sample size

233

100

Gender

< 1 year

11

4.7

1–9 years

160

68.7

> 10 years

62

26.6

Sex

Female

113

48.5

Male

120

51.5

WBC (× 109/l)

< 50

164

70.4

50–100

28

12.0

> 100

38

16.3

No data

3

1.3

Protocol

TPOG 2002

108

46.4

TPOG 2013

125

53.6

Early treatment responsea

MRD positive

30

27.0

MRD negative

81

73.0

Subtype

Hyperdiploidy

59

25.3

Hypodiploidy

7

3.0

ETV6-RUNX1

36

15.5

TCF3-PBX1

12

5.2

Ph+/Ph-like

16

6.9

KMT2A-r

14

6.0

ZNF384/362-r

9

3.9

MEF2D-r

3

1.3

TCF3-HLF

2

0.9

iAMP21

4

1.7

Other

71

30.5

  1. aOnly patients treated with TPOG-2013 were included (n = 111). Fourteen patients were excluded due to missing data; MRD positive: either MRD > 1% at day 15 or > 0.01% at day 35.
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