Table 4 Receiver operating characteristic area under the curve (95% confidence intervals) for prediction of outcome in high risk women, using CVF elafin concentration stratified by gestation at sampling, after exclusion of samples taken once prophylactic intervention had been initiated.

From: Cervicovaginal natural antimicrobial expression in pregnancy and association with spontaneous preterm birth

Outcome

Elafin receiver operating characteristic area under the curve (95% confidence interval)

Gestation category (weeks+days)

10–13+6

14–15+6

16–19+6

20–24+0

Cervical shortening < 25 mm

0.60 (0.53–0.66)

0.48 (0.42–0.55)

0.49 (0.43–0.56)

0.53 (0.46–0.60)

sPTB < 37 w

0.49 (0.42–0.56)

0.48 (0.41–0.55)

0.48 (0.41–0.55)

0.52 (0.44–0.59)

sPTB < 34 w

0.63 (0.56–0.70)

0.61 (0.54–0.67)

0.57 (0.50–0.63)

0.64 (0.58–0.71)

PPROM

0.54 (0.47–0.61)

0.52 (0.45–0.59)

0.49 (0.42–0.56)

0.61 (0.53–0.67)

Objective infection

0.49 (0.42–0.56)

0.49 (0.42–0.55)

0.50 (0.43–0.56)

0.53 (0.46–0.60)

Fetal adverse outcomes

0.60 (0.53–0.67)

0.50 (0.44–0.58)

0.48 (0.42–0.55)

0.52 (0.45–0.59)

  1. Values in bold are statistically significant at p < 0.05.