Tabel 1 p-values of the Parkinson-, of the metallothionein-, of the paralysis- and the lifespan assay using student’s t-test.
Compound | Strain | ||||
|---|---|---|---|---|---|
CL2120 | CL2659 | NL5901 | CL2659-MT | N2 | |
1% DMSO | 1 | 1 | 1 | 1 | 1 |
100 µM ZnSO4 | 0.013 | 0.015 | 0.778 | 0.002 | 0.738 |
10 µM ZnSO4 | n.t | 0.124 | n.t | 0.011 | 0.017 |
2 mM levodopa | 0.773 | 0.012 | 0.001 | 0.531 | n.t |
100 µM clioquinol | 0.038 | 0.018 | 0.037 | 0.001 | 0.085 |
50 µM clioquinol | n.t | 0.018 | n.t | 0.001 | n.t |
10 µM clioquinol | 0.018 | 0.010 | 0.013 | 0.002 | 0.011 |
1 µM clioquinol | 0.245 | n.t | 0.049 | n.t | |
100 µM thioflavin T | 0.011 | 0.018 | 0.000 | 0.000 | 0.003 |
50 µM thioflavin T | n.t | 0.018 | n.t | 0.001 | n.t |
10 µM thioflavin T | 0.035 | 0.010 | 0.201 | 0.036 | 0.009 |
1 µM thioflavin T | 0.045 | n.t | 0.063 | n.t | n.t |
100 µM apomorphin | 0.044 | 0.005 | 0.006 | n.t | 0.085 |
10 µM apomorphine | 0.013 | 0.009 | 0.025 | n.t | 0.009 |
1 µM apomorphine | 0.163 | n.t | 0.018 | n.t | n.t |
300 µM dexamethason | 0.030 | 0.177 | 0.328 | n.t | 0.662 |
30 µM dexamethason | 0.035 | 0.005 | 0.584 | n.t | 0.317 |
3 µM dexamethason | 0.056 | n.t | 0.183 | n.t | n.t |
300 µM quercetin | 0.067 | 0.128 | 0.149 | n.t | 0.051 |
33 µM quercetin | 0.018 | 0.011 | 0.007 | 0.011 | 0.076 |
3.3 µM quercetin | 0.136 | n.t | 0.010 | n.t | n.t |
0.3 µM sesamin | 0.005 | 0.002 | 0.052 | n.t | n.t |
56 µM sesamin | n.t | n.t | n.t | 0.342 | n.t |
28 µM sesamin | 0.055 | 0.008 | 0.109 | 0.155 | n.t |
2.8 µM sesamin | 0.965 | 0.123 | 0.339 | 0.138 | n.t |
400 µM emodin | 0.008 | 0.0.003 | 0.0.014 | n.t | 0.087 |
74 µM emodin | n.t | 0.023 | n.t | 0.011 | n.t |
37 µM emodin | 0.018 | 0.015 | 0.018 | 0.040 | 0.020 |
3.7 µM emodin | 0.002 | 0.432 | 0.187 | 0.014 | n.t |