Figure 5

Quantification of c-Fos positive nuclei in central structures sensitive to DON treatment. LC, locus coeruleus; LHA, lateral hypothalamic area; LPB, lateral parabrachial nucleus; PVN, paraventricular nucleus; NTS, nucleus tractus solitarius; SON, supra optic nucleus; VLM, caudal ventrolateral medulla; VMH, ventromedial hypothalamus. Significances were determined relative to control animals. Comparisons between data from vehicle and DON-treated mice were performed using unpaired 2-tailed Student’s t test. **P < 0.01 and ***P < 0.001 significantly different from control mice.