Table 1 The demographic characteristics of the study population.

From: Alteration of immunophenotype of human macrophages and monocytes after exposure to cigarette smoke

Severity GOLD GRADE

Age (years)

Gender (M/F)

FEV1 (% Pred)

Current smoke (Y/N)

Normal

(50–70)

(5/3)

 ≥ 80

(0/8)

COPD-1

70 (56–85)

(11/5)

 ≥ 80

(2/14)

COPD-2

66 (53–87)

(11/9)

60.7 (51–77)

(7/13)

COPD-3

66 (54–83)

(6/4)

40.1 (31–49)

(3/7)

COPD-4

65 (56–79)

(5/0)

20.8 (23–29)

(0/5)

  1. Patients with COPD were recruited by the Department of Pulmonology and Urology at Pedro Ernesto University Hospital. Patients with COPD had to have a forced expiratory volume in 1 s (FEV1) of between 30 and 80% predicted, were aged 50 or over, and had a spirometry-proven diagnosis of COPD and a smoking burden of more than 20 pack-years. An obstructive pulmonary disorder corresponds to an FEV1 (forced first–second expiratory volume)/forced vital capacity (FVC) ratio of less than 0.7 after the use of salbutamol 400 µg. The control group comprised individuals aged 50 or over, with normal spirometry and chest X-ray results and no airflow obstructions.
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