Figure 6
From: Effects of progranulin on the pathological conditions in experimental myocardial infarction model
Administration of recombinant progranulin decreased myocardial fibrosis size after myocardial ischemia–reperfusion in rabbits. (A) Representative photographs show LV cross-sections stained by Masson’s trichrome solutions 2 weeks after myocardial I/R. (B) Quantitative analysis of fibrosis size 2 weeks after myocardial I/R. The administration of recombinant progranulin significantly reduced fibrosis size compared with vehicle-treated group. Scale bar: 2.5 mm. Data are the means ± SEM. (n = 3–7) *p < 0.05 versus vehicle-treated group (one-tailed Student's t-test).
