Figure 1 | Scientific Reports

Figure 1

From: Conditional and unconditional genome-wide association study reveal complicate genetic architecture of human body weight and impacts of smoking

Figure 1

Genetic architecture of highly significant SNPs at the experiment-wise level (PEW < 10–5) for body weight in two models. WT = the base model with no cofactor (left box). WT|SMK = the conditional model on smoking (right box). The left axis is the SNP IDs (Chromosome_SNP_Allele), and each line represents a SNP. The different shape symbols on each line represent the different effects of that SNP: Circle = additive effect; Square = dominance effect; Black color = only epistasis effects (not include single effects); Red color = general effects for four ethnic groups; Green color = ethnicity-specific effects; Blue color = both general and ethnicity-specific effects; Lines = epistasis effect of two SNPs, and the color of the lines have the same meaning as above.

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