Figure 3
From: Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
The effects of FeH on gene expressions of macrophages. (A–L) qRT-PCR of FeH (A), FeL (B), IL-1β (C), IL-6 (D), IL-10 (E), IL-12 (F), TNF-α (G), TGF-β (H), VEGF (I), NLRP3 (L). The FeH stimulation of macrophages for both 120 and 240 min, does not change the gene expression of TGF-β and VEGF. The gene expressions of FeH and FeL significantly decrease after FeH stimulation, for 120 min. The gene expressions of IL-1β, IL-6, IL-10, TNF-α, IL-12 and NLRP3 significantly increase after FeH stimulation. Any single dot, in the figure, represents the median of triplicate experiments (* = p = 0.02; ** = p ≤ 0.008).
