Figure 7
From: Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
Effects of ferritin, FeH and FeL on the proliferation of PBMCs co-cultured with macrophages. (A–C) PBMCs proliferation using MTS assay. (A) The picture shows the absorbance of untreated PBMCs (circle), PBMCs treated with LPS (square), PBMCs treated with LPS and co-cultured with untreated macrophages (triangle up), PBMCs stimulated with LPS and co-cultured with macrophages stimulated with ferritin (triangle down). Any single dot, in the figure, represents the median of triplicate experiments (* = p = 0.02; *** = p < 0.0001). (B) The picture shows the absorbance of untreated PBMCs (circle), PBMCs treated with LPS (square), PBMCs treated with LPS and co-cultured with untreated macrophages (triangle up), PBMCs stimulated with LPS and co-cultured with macrophages stimulated with FeH (triangle down). Any single dot, in the figure, represents the median of triplicate experiments (* = p = 0.02; *** = p < 0.0001). (C) The picture shows the absorbance of untreated PBMCs (circle), PBMCs-treated with LPS (square), PBMCs treated with LPS and co-cultured with untreated macrophages (triangle up), PBMCs stimulated with LPS and co-cultured with macrophages stimulated with FeL (triangle down). Any single dot, in the figure, represents the median of triplicate experiments (*** = p = 0.0002).
