Figure 3
From: Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity
Ant34a upregulates cardiac expression of Bcl-2 and SIRT1 in DOXO treated rats. (a) Bcl-2 mRNA and protein levels were evaluated by qPCR and western blot analysis respectively. (b) SIRT1 mRNA and protein levels were evaluated by qPCR and western blot analysis respectively. (c) Representative images of western blot protein bands. Full-length blots are displayed in Supplementary Fig. S1a–b. mRNA and protein expressions are shown as fold change with respect to CTL group. Results are presented as mean ± SD, n = 5–8/group. *p < 0.05 vs CTL; °p < 0.05 vs DOXO; #p < 0.05 vs D + AntCTL. D: DOXO.
