Table 1 Population characteristics with unadjusted geometric mean (GM) and 95% confidence interval (95% CI) of wet-weight BDE-47 levels in maternal, placental, and fetal liver tissues among pregnant women during mid-gestation at the Women's Options Center (WOC) in Northern California (study waves 3–4; 2014–16; n = 180)
Characteristic | n (%) | Fetal liver BDE-47 (ng/g) | p-value | BDE-47 (ng/g) | p-value | Maternal serum BDE-47 (ng/ml) | p-value |
|---|---|---|---|---|---|---|---|
Maternal age | |||||||
< 20 years | 27 (15) | 0.32 (0.23, 0.44) | 0.764 | 0.12 (0.09, 0.15) | 0.81 | 0.17 (0.13, 0.22) | 0.329 |
20–24 years | 74 (41) | 0.29 (0.20, 0.43) | 0.12 (0.09, 0.15) | 0.20 (0.14, 0.27) | |||
25–29 years | 42 (23) | 0.27 (0.18, 0.42) | 0.11 (0.08, 0.15) | 0.18 (0.13, 0.25) | |||
≥ 30 years | 37 (21) | 0.30 (0.19, 0.47) | 0.11 (0.08, 0.15) | 0.16 (0.11, 0.23) | |||
Body mass index (BMI) | |||||||
Normal/under (< 25 kg/m2) | 79 (44) | 0.27 (0.22, 0.32) | 0.310 | 0.11 (0.09, 0.13) | 0.697 | 0.17 (0.15, 0.20) | 0.834 |
Overweight (25–30 kg/m2) | 52 (29) | 0.29 (0.22, 0.40) | 0.12 (0.10, 0.15) | 0.18 (0.14, 0.23) | |||
Obese (≥ 30 kg/m2) | 49 (27) | 0.34 (0.25, 0.46) | 0.11 (0.09, 0.14) | 0.19 (0.15, 0.24) | |||
Birth country | |||||||
U.S. born | 105 (58) | 0.28 (0.24, 0.33) | 0.045* | 0.13 (0.11, 0.14) | 0.014* | 0.18 (0.16, 0.20) | 0.055 |
Foreign born | 16 (9) | 0.15 (0.10, 0.25) | 0.08 (0.06, 0.11) | 0.12 (0.08, 0.16) | |||
Education | |||||||
≤ High school | 86 (48) | 0.32 (0.27, 0.39) | 0.423 | 0.12 (0.11, 0.14) | 0.298 | 0.21 (0.18, 0.24) | 0.022* |
≥ Some college | 93 (52) | 0.27 (0.21, 0.35) | 0.11 (0.09, 0.13) | 0.16 (0.13, 0.19) | |||
Employment | |||||||
Employed | 70 (39) | 0.26 (0.21, 0.32) | 0.855 | 0.10 (0.09, 0.12) | 0.936 | 0.18 (0.15, 0.21) | 0.559 |
Unemployed | 73 (41) | 0.28 (0.21, 0.38) | 0.10 (0.08, 0.12) | 0.20 (0.16, 0.25) | |||
Gestational age | |||||||
< 19 weeks | 47 (26) | 0.37 (0.29, 0.47) | 0.102 | 0.12 (0.10, 0.14) | 0.811 | 0.18 (0.15, 0.22) | 0.989 |
≥ 19 weeks | 133 (74) | 0.27 (0.20, 0.36) | 0.11 (0.09, 0.14) | 0.18 (0.14, 0.23) | |||
Insurance | |||||||
Public | 136 (76) | 0.32 (0.28, 0.37) | 0.011* | 0.12 (0.11, 0.13) | 0.037* | 0.19 (0.17, 0.21) | 0.509 |
Private/self-pay | 39 (22) | 0.20 (0.15, 0.27) | 0.09 (0.07, 0.11) | 0.16 (0.13, 0.20) | |||
Parity | |||||||
0 prior live births | 73(41) | 0.24 (0.20, 0.29) | 0.055 | 0.10 (0.08, 0.11) | 0.032* | 0.15 (0.13, 0.17) | 0.011* |
≥ 1 prior live births | 107 (59) | 0.33 (0.26, 0.43) | 0.13 (0.10, 0.15) | 0.20 (0.17, 0.25) | |||
Race/ethnicity | |||||||
Latina/Hispanic | 67 (37) | 0.30 (0.24, 0.37) | 0.063 | 0.12 (0.10, 0.14) | 0.104 | 0.19 (0.16, 0.22) | 0.021* |
Non-Hispanic Black | 47 (26) | 0.28 (0.20, 0.39) | 0.12 (0.09, 0.15) | 0.18 (0.14, 0.24) | |||
Non-Hispanic White | 40 (22) | 0.36 (0.26, 0.51) | 0.12 (0.09, 0.15) | 0.20 (0.15, 0.26) | |||
Asian/Pacific Islander/Other | 26 (14) | 0.22 (0.15, 0.32) | 0.09 (0.07, 0.12) | 0.13 (0.09, 0.17) | |||
Region of residence | |||||||
SF Bay Area | 99 (55) | 0.26 (0.22, 0.30) | 0.103 | 0.11 (0.09, 0.12) | 0.395 | 0.17 (0.15, 0.19) | 0.016* |
S. Central Valley/Fresno | 24 (13) | 0.38 (0.26, 0.55) | 0.13 (0.10, 0.17) | 0.25 (0.19, 0.34) | |||
N. Central Valley/Coast/Sierras | 39 (22) | 0.31 (0.23, 0.43) | 0.12 (0.09, 0.15) | 0.17 (0.13, 0.21) | |||
Fetal sex | |||||||
Male | 92 (51) | 0.30 (0.25, 0.35) | 0.978 | 0.11 (0.10, 0.13) | 0.956 | 0.18 (0.16, 0.21) | 0.997 |
Female | 85 (47) | 0.29 (0.22, 0.37) | 0.11 (0.09, 0.13) | 0.18 (0.15, 0.22) | |||
Collection year | |||||||
2014 | 81 (45) | 0.39 (0.33, 0.47) | < 0.001** | 0.13 (0.12, 0.15) | 0.001** | 0.17 (0.14, 0.20) | 0.496 |
2015 | 91 (51) | 0.22 (0.17, 0.29) | 0.10 (0.08, 0.11) | 0.19 (0.15, 0.23) | |||
2016 | 8 (6) | 0.32 (0.18, 0.59) | 0.16 (0.10, 0.26) | 0.19 (0.12, 0.32) | |||