Table 2 Comparison of inhibitory activity (IC50) of each IDP and crowding agent on Aβ(1–42) fibril formation.

From: Presence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1–42) in amino acid sequence independent manner

IDP

IC50 (µM)

B4

90

C1

68

D10

6.8

E1

130

FK20

82

PEG6000

4,100

DEX6

7,700