Figure 3

Screening of positive controls. Bar charts of mean DT50 values of C. elegans treated with mianserine (50 µM), reserpine (30 µM) and caffeine (50 µM) in comparison to vehicle control. Reserpine at 30 µM significantly extended the DT50 of wild type C. elegans by 31.4%. Bars represent the DT50 value in comparison to the control group ± SD of three parallel experiments. Significance was assessed by one way ANOVA with Dunnett post-test (*p < 0.05).