Table 4 [Ca 2+1ex dose response with 60 mM [Na+]ex (Figs. 4, 10; Supplementary Figures S31, S7).

From: Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in CaV3 T-type channels alter the passage and block of monovalent and divalent ions

In mM

Ca2+ free

CaCI2

NaCI

EGTA

HEPES

Glucose

Externala

1

1 × 10−9

0.01

60

1.246

10

26.3

2

1 × 10−7

1.00

60

2.236

10

20.4

3

1 × 10−5

1.00

60

1.002

10

24.1

4

1 × 10−4

0.10

60

0

10

29.7

5

3 × 10−4

0.30

60

0

10

29.1

6

1 × 10−3

1.00

60

0

10

27.0

7

3 × 10−3

3.00

60

0

10

21.0

8

1 × 10−2

10.00

60

0

10

0.0

CsCI

EGTA

Mg-ATP

Li-GTP

HEPES

Internalsb

110

10

3

0.6

10

  1. apH 7.4 with TEA-OH.
  2. bpH 7.4 with CsOH.