Table 1 Association statistics for genome-wide significant SNPs.
rsID | Position | Gene | RA | RAF NMO (n = 119) | RAF Ctrl (n = 1,208) | Unconditioned | Conditioned on rs9272219 | UTS/ACP data set | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR | P | ||||||
rs9368726 | 32,438,542 | HLA-DRB9 | A | 0.80 | 0.61 | 2.70 (1.92–3.70) | 1 × 10–8 | 1.75 (1.09–2.86) | 0.022 | 2.22 | 8 × 10–9 |
rs9405108 | 32,438,648 | HLA-DRB9 | G | 0.80 | 0.61 | 2.70 (1.92–3.85) | 8 × 10–9 | 1.75 (1.08–2.86) | 0.023 | 2.22 | 8 × 10–9 |
rs1964995 | 32,449,411 | Intergenic | A | 0.78 | 0.56 | 2.63 (1.92–3.70) | 5 × 10–9 | 1.79 (1.09–2.94) | 0.023 | – | – |
rs9271588 | 32,590,953 | Intergenic | A | 0.75 | 0.53 | 2.63 (1.92–3.57) | 2 × 10–9 | 1.75 (1.05–2.86) | 0.032 | 1.96 | 1 × 10–9 |
rs9272219 | 32,602,269 | HLA-DQA1 | A | 0.67 | 0.42 | 2.48 (1.86–3.32) | 8 × 10–10 | – | – | – | – |
rs9273012 | 32,611,641 | HLA-DQA1 | G | 0.67 | 0.42 | 2.49 (1.86–3.32) | 8 × 10–10 | – | – | – | – |
