Table 2 Over-representation analysis of co-expressed genes with hub miRNA using EO-PCa data.

From: Identification of candidate miRNAs in early-onset and late-onset prostate cancer by network analysis

hub miRNA

Gene set

Size

Expect

Ratio

Overlap

FDR

hsa_miR_142_5p

WALLACE PROSTATE CANCER RACE UP

277

3.64

4.12

15

1.0889E−06

hsa_miR_150_5p

WALLACE PROSTATE CANCER RACE UP

277

2.32

3.88

9

8.83E−04

hsa_miR_142_5p

Ding Early onset prostate cancer 2016

158

2.08

5.78

12

1.0889E−06

hsa_miR_150_5p

Ding Early onset prostate cancer 2016

158

1.32

6.81

9

1.46E−05

hsa_miR_146b_3p

Ding Early onset prostate cancer 2016

158

6.89

4.93

34

3.12E−13

hsa_miR_3545_3p

LIU PROSTATE CANCER DN

473

5.65

2.30

12

0.015

  1. Only statistically significant associations are shown. Size means the number of genes in the pathway. Expect means the expected number of genes in the pathway co-expressed by chance with the miRNA. Ratio means the additional number of times that there are more genes co-expressed with the miRNA compared with the expected number. Overlap means the number of co-expressed genes that are part of the pathway. FDR is the false discovery rate of the overlap.
Back to article page