Table 1 Demographics and clinical characteristics of the patient sample according to BPD and PH status.

From: Soluble Klotho, a biomarker and therapeutic strategy to reduce bronchopulmonary dysplasia and pulmonary hypertension in preterm infants

 

Control (n = 15)

BPD (n = 11)

BPD–PH (n = 14)

P value

Infant characteristics

Gestational age (weeks)

27.5 ± 1

26.1 ± 1.5

27 ± 1

0.02

Birth weight (grams)

1,081 ± 197

940 ± 127

901 ± 173

0.02

Birth weight percentile

67 ± 24

73 ± 23

55 ± 29

NS

Male sex (%)

6 (40)

8 (73)

4 (29)

NS

Maternal characteristics

Maternal age (years)

28.2 ± 7.2

31.1 ± 5.9

32.1 ± 6.2

NS

Maternal race

 Black

5 (33)

0

2 (14)

NS

 White

5 (33)

6 (55)

9 (64)

 Asian

0

0

2 (14)

 Hispanic

4 (27)

5 (45)

1 (7)

 Other/unknown

1 (6)

0

0

Preterm labor (%)

10 (67)

10 (91)

11 (79)

NS

Premature rupture of membranes (%)

6 (40)

5 (45)

4 (29)

NS

Prolonged rupture of membranes (%)

5 (33)

4 (36)

4 (29)

NS

Cesarean section (%)

8 (53)

9 (82)

12 (86)

NS

Antenatal steroids (%)

14 (93)

11 (100)

13 (93)

NS

Preeclampsia (%)

3 (20)

1 (9)

3 (21)

NS

Chrorioamnionitis (%)

3 (20)

1 (9)

1 (7)

NS

Non-reassuring fetal heart tones (%)

2 (13)

1 (9)

1 (7)

NS

Apgar 1 min (mean)

6 + 1.9

3.6 + 2.2

3.9 + 2.5

0.02

Apgar 5 min (mean)

7.9 ± 0.7

6.4 ± 1.4

5.7 ± 2.6

0.005