Table 3 Comparison of septic versus non-septic burn patients.

From: Novel application of an automated-machine learning development tool for predicting burn sepsis: proof of concept

Variable

Septic (n = 92)

Non-septic (n = 119)

P-value

A. Demographics

Mean (SD) age (years)

44.5 (18.1)

38.6 (15.7)

NS

Mean (SD) TBSA (%)

38.9 (16.9)

21.7 (10.8)

0.033

Gender (M/F)

59/33

80/39

NS

Inhalation injury (%)

14.1%

13.9%

NS

ICU LOS (days)

58.7 (25.6)

40.2 (26.2)

0.021

Median (IQR) # infections per patient

 Bloodstream

5.5 (6.0)

N/A

N/A

 Pneumonia

7.2 (5.5)

N/A

N/A

 Urinary tract

3.6 (2.7)

N/A

N/A

 Wound

4.4 (3.6)

N/A

N/A

 Mortality (%)

31.5

11.8

0.001

 Mean GCS (SD)

10.3 (2.8)

11.4 (2.8)

0.005

 Mean (SD) MODS

4.4 (2.8)

3.9 (2.7)

0.006

 Mean (SD) SOFA

4.1 (2.7)

3.2 (2.3)

< 0.001

B. Laboratory data

Median Temperature (IQR) (ºC)

39.2 (4.0)

38.0 (3.5)

0.010

Median HCT (IQR) (%)

24.0 (7.0)

25.5 (8.6)

0.003

Median HGB (IQR) (g/dL)

7.8 (2.2)

8.5 (3.0)

< 0.001

Median WBC (IQR) (cells/µL)

13.1 (10.7)

12.1 (9.0)

0.001

Median creatinine (IQR) (mg/dL)

0.80 (0.91)

0.71 (0.38)

< 0.001

Median BUN (IQR) (mg/dL)

21 (20.8)

13 (9.8)

< 0.001

Mean Na+ (SD) (mmol/L)

139.2 (5.28)

136.8 (4.53)

< 0.001

Mean TCO2 (SD) (mmol/L)

26.8 (4.9)

24.8 (3.68)

0.001

Median PLT (IQR) (cells/µL)

289 (300.5)

352.5 (344.8)

< 0.001

  1. BUN blood urea nitrogen, HCT hematocrit, HGB hemoglobin, ICU intensive care unit, F female, GCS Glascow Coma Score, IQR interquartile range, LOS length-of-stay, M male, MODS multiple organ dysfunction score, N/A not applicable, Na+ ionized sodium, NS not significant, PLT platelet count, SD standard deviation, SOFA sequential organ failure assessment score, TBSA total body surface area, TCO2 total CO2, and WBC white blood cell count.