Figure 2 | Scientific Reports

Figure 2

From: Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets

Figure 2

Sex differences in the endothelial transcriptome at birth. (A) Histograms of adjusted p-values are shown for both the boy–boy/girl–girl twins (green) and the boy–girl twins in which can be corrected for mother (red). (B) The number of differential genes per chromosome is shown in percentages of all genes interrogated on that chromosome (top for boy–boy/girl–girl twins, bottom for boy–girl twins). Lightgrey indicates higher expression in males (notice the Y-chromosome), darkgrey indicates higher expression in females. (C) Hallmark gene enrichments are shown in a radar plot. Blue highlights the significance of the gene enrichment of genes higher expressed in males, whereas pink shows this for genes higher expressed in females. The length of the radius measures significance (− log10 adjusted p-value).

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