Table 1 Characteristics of study populations.
From: Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism
RS GEN2 n = 943 | TwinsUK n = 1598 | ||
|---|---|---|---|
Demographic characteristics | Age in years (range) | 20.0 (18.3–22.1) | 62.6 (21.7–89.7) |
Sex (female) | 488 (52%) | 1,455 (91%) | |
Genotypic characteristics | rs33912345 | ||
Genotype A/A | 338 (35.8%) | 545 (34.1%) | |
Genotype A/C | 466 (49.4%) | 774 (48.4%) | |
Genotype C/C | 139 (14.7%) | 279 (17.5%) | |
rs10483727 | |||
Genotype C/C | 334 (35.4%) | 548 (34.3%) | |
Genotype C/T | 478 (50.7%) | 772 (48.3%) | |
Genotype T/T | 131 (13.9%) | 278 (17.4%) | |
Ocular characteristics | Peripapillary RNFL thickness (μm) | ||
Global | 100.4 ± 9.8 | 95.5 ± 9.9 | |
Inferior sector | 126.7 ± 16.9 | 119.0 ± 14.9 | |
Superior sector | 124.3 ± 15.8 | 115.3 ± 14.4 | |
Nasal sector | 79.3 ± 13.8 | 75.4 ± 13.1 | |
Temporal sector | 71.3 ± 10.4 | 72.1 ± 9.4 | |
Central corneal thickness (μm) | 539.0 ± 32.5 | 539.6 ± 35.7 | |
Intraocular pressure (mmHg) | 15.5 ± 3.2 | 13.4 ± 3.1 | |
Spherical equivalent (D) | 0.00 ± 1.44 | 0.22 ± 2.6 | |
