Table 2 Peripapillary RNFL thickness by SIX1/SIX6 region variant genotypes.
From: Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism
Global | Inferior sector | Superior sector | Nasal sector | Temporal sector | |
|---|---|---|---|---|---|
rs33912345 RS GEN2 | |||||
A/A (n = 338) | 100.9 ± 10.1 | 127.3 ± 17.7 | 125.3 ± 16.0 | 79.4 ± 14.0 | 71.5 ± 10.0 |
A/C (n = 466) | 100.3 ± 9.6 | 126.5 ± 16.3 | 123.5 ± 15.5 | 79.7 ± 13.8 | 71.2 ± 10.8 |
C/C (n = 139) | 99.9 ± 10.0 | 125.7 ± 17.0 | 124.8 ± 16.3 | 77.6 ± 13.7 | 71.3 ± 10.1 |
p value* | 0.560 | 0.611 | 0.258 | 0.279 | 0.898 |
TwinsUK | |||||
A/A (n = 545) | 95.5 ± 9.8 | 118.8 ± 15.2 | 115.7 ± 14.7 | 74.8 ± 12.5 | 72.8 ± 10.0 |
A/C (n = 774) | 95.8 ± 9.6 | 119.5 ± 14.9 | 115.6 ± 13.9 | 76.1 ± 13.1 | 72.0 ± 9.0 |
C/C (n = 279) | 95.5 ± 10.5 | 119.0 ± 15.2 | 114.9 ± 14.2 | 76.9 ± 13.8 | 71.2 ± 9.8 |
p value* | 0.830 | 0.692 | 0.726 | 0.061 | 0.063 |
rs10483727 RS GEN2 | |||||
C/C (n = 334) | 101.0 ± 10.1 | 127.4 ± 17.7 | 125.4 ± 15.9 | 79.4 ± 13.8 | 71.6 ± 10.1 |
C/T (n = 478) | 100.3 ± 9.7 | 126.4 ± 16.3 | 123.5 ± 15.5 | 79.7 ± 13.9 | 71.1 ± 10.7 |
T/T (n = 131) | 99.9 ± 10.0 | 125.8 ± 17.2 | 124.6 ± 16.6 | 77.4 ± 13.4 | 71.4 ± 10.0 |
p value* | 0.460 | 0.556 | 0.242 | 0.243 | 0.798 |
TwinsUK | |||||
C/C (n = 548) | 95.6 ± 9.8 | 118.9 ± 15.1 | 115.8 ± 14.5 | 74.9 ± 12.4 | 72.7 ± 10.0 |
C/T (n = 772) | 95.7 ± 9.7 | 119.4 ± 15.0 | 115.4 ± 13.9 | 75.9 ± 13.2 | 72.0 ± 9.0 |
T/T (n = 278) | 95.6 ± 10.5 | 119.1 ± 15.2 | 115.0 ± 14.3 | 77.1 ± 13.7 | 71.3 ± 9.9 |
p value* | 0.980 | 0.835 | 0.733 | 0.067 | 0.121 |
