Table 2 Univariate and multivariate logistic regression analysis of serum adipokines and other risk factors of hepatic steatosis after liver transplantation.

From: Hepatic steatosis and liver fat contents in liver transplant recipients are associated with serum adipokines and insulin resistance

 

Univariate analysis

Multivariate analysis

With steatosis

Without steatosis

P-value

Odds ratio

95% CI

P-Value

Age (year)

47.30 ± 11.76

42.36 ± 12.90

0.009

1.020

0.935–1.027

0.402

Men/women, n (%)

50 (63)/29 (37)

49 (49)/50 (51)

0.057

   

BMI (Kg/m2)

27.58 ± 5.02

24.08 ± 11.38

0.014

1.006

0.932–1.088

0.883

WC (cm)

101.50 ± 11.92

88.67 ± 9.15

 < 0.001

1.013

0.896–1.141

0.856

HC (cm)

108.88 ± 11.07

97.84 ± 7.61

 < 0.001

1.058

0.936–1.196

0.369

Triglyceride (mg/dL)

178.40 ± 87.36

124.20 ± 66.28

 < 0.001

1.005

0.996–1.014

0.278

HDL (mg/dL)

42.64 ± 12.66

48.34 ± 16.51

0.021

1.003

0.956–1.039

0.997

Cholesterol (mg/dL)

181.41 ± 55.96

166.03 ± 53.18

0.085

   

LDL (mg/dL)

97.55 ± 36.38

90.63 ± 35.61

0.076

   

FBS (mg/dL)

129.77 ± 52.19

104.14 ± 36.42

 < 0.001

   

AST (IU/L)

23.92 ± 11.88

32.51 ± 34.38

0.059

   

ALT (IU/L)

27.22 ± 13.01

39.30 ± 50.98

0.068

   

Time to study (months)

42.21 ± 36.05

35.76 ± 32.98

0.216

   

PTDM, n (%)

41 (53.2)

24 (25)

 < 0.001

5.988

1.680–21.276

0.006

HTN, n (%)

24 (32.4)

17 ( 18.3)

0.035

1.729

0.548–5.458

0.381

HLP, n (%)

33 (43.4)

18 (18.8)

 < 0.001

0.430

0.102–1.808

0.250

NASH, n (%)

24 (30.4)

9 (9.4%)

 < 0.001

0.802

0.171–3.747

0.779

Adiponectin (µg/ml)

13.30 ± 10.59

24.91 ± 17.42

 < 0.001

0.912

0.869–0.957

 < 0.001

Leptin (ng/ml)

20.64 ± 22.02

9.97 ± 11.97

 < 0.001

1.060

1.017–1.102

0.005

Insulin (µU/ml)

15.82 ± 17.73

8.80 ± 7.07

 < 0.001

   

HOMA2-IR

2.04 ± 1.80

1.20 ± 0.87

 < 0.001

1.671

1.049–2.662

0.031

  1. BMI Body mass index, WC waist circumference, HC Hip circumference, PTDM post transplant diabetes mellitus, HLP Hyperlipidemia, HTN Hypertension, HOMA-IR Homeostatic model for insulin resistance, FBS Fasting blood sugar, AST Aspartate aminotransferase, ALT Alanine aminotransferase, NASH non-alcoholic steatohepatitis, HDL High density lipoprotein, LDL Low density lipoprotein.