Figure 1 | Scientific Reports

Figure 1

From: Inhibition of acetyl-CoA carboxylase by spirotetramat causes growth arrest and lipid depletion in nematodes

Figure 1

Effect of SPT-enol on C. elegans development. (A) Time course experiment on survival rate of non-developing and arrested C. elegans nematodes. The data are given in average ± SD (n = 3). For each time point, Student’s t-test was performed for SPT-enol + against DMSO (control) and SPT-enol + against SPT-enol—(*P < 0.001). (B) Concentration-dependent effect of SPT-enol on C. elegans larval arrest. The data are given in average ± SD (n = 3). For each concentration of SPT-enol, Student’s t-test was performed for SPT-enol against DMSO (control) (*P < 0.001). (C) Recovery of non-developing L1 larvae and SPT-enol-arrested larvae of C. elegans. The data are given in average ± SD (n = 3). Student’s t-test was performed for SPT-enol 200 µM + against DMSO (control) and SPT-enol 200 µM + against SPT-enol 200 µM—(*P < 0.001). In these experiments, ( +) and (−) indicate presence or absence of a food source. DMSO plus food source was excluded from the analysis since larvae develop into adults under these conditions.

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