Figure 4
From: MITF variants cause nonsyndromic sensorineural hearing loss with autosomal recessive inheritance
Subcellular localization of wild-type and mutant MITF proteins. The studied proteins are in green (left panel), DAPI-stained nuclei are shown in blue (middle panel), and the merged images are shown on the right panel. Note the nuclear localization of the wild-type MITF and the exclusively cytosolic localization of the R341C (Arg341Cys) and R341H (Arg341His) variants.
