Figure 1
From: FOSL1 is a novel mediator of endotoxin/lipopolysaccharide-induced pulmonary angiogenic signaling
RNA-seq data from lung endothelial cells isolated from DOL-4 mice treated with LPS for 6 h. (A) Heatmap of differentially expressed genes (n = 3); (B) top pathways identified in Ingenuity Pathway Analysis as activated; and (C) validation RT-PCR in primary mouse lung endothelial cells (n = 6). Data presented at mean ± standard deviation, *p < 0.001 between LPS-treated and saline control baseline by one-sample, two-tailed Student’s t test as all data were normally distributed. Graphs created in SPSS 26 for Mac (https://www.ibm.com/analytics/spss-statistics-software) and image assembled in Adobe Illustrator 24.1.0 for Mac (https://www.adobe.com/products/illustrator.html).
