Figure 2

Variable importance in the projection (VIP) plots of adult mice exposed to early life stress (n = 14) and controls (n = 9), showing the relative contribution of metabolites. (A) Kidney tissues. (B) Heart tissues. High variable importance in the projection values indicate greater contribution of these metabolites to group separation, shown in the PLS-DA plots. Green and red boxes indicate relative metabolite concentration. A score of 1.0 is considered able to discriminate between two phenotypes.