Figure 6 | Scientific Reports

Figure 6

From: A lncRNA landscape in breast cancer reveals a potential role for AC009283.1 in proliferation and apoptosis in HER2-enriched subtype

Figure 6

(A) Early apoptosis cells were observed to be significantly different between shRNA NC and shRNA2 AC009283.1 using flow cytometry assay on SKBR-3 cells. (B) Analysis that represents the percentage of cells in early apoptosis in three biological assays on SKBR-3 cells. *p < 0.05, **p < 0.005, ***p < 0.0005, compared with shRNA NC for each condition via Student’s t test. (C) Quantitative analysis of caspase-3 activity of cells treated with shRNA NC and shRNA2 AC009283.1, units are defined as the amount of enzyme that cleaves 1 nm colorimetric substrate/h. QBS 50uM was used as the positive control for apoptosis. *p < 0.05, **p < 0.005, ***p < 0.0005, compared with shRNA NC for each condition using Student’s t test.

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