Figure 7 | Scientific Reports

Figure 7

From: A lncRNA landscape in breast cancer reveals a potential role for AC009283.1 in proliferation and apoptosis in HER2-enriched subtype

Figure 7The alt text for this image may have been generated using AI.

(A) Top 5 lncRNAs expressed in 17q12-21.3 vs copy number changes. (B) Expression of AC009283.1 in BRCA subtypes including hormone receptor and HER2 receptor status. (C) Bubble plot representing GSEA analysis in AC009283.1 high expression breast cancer samples versus AC009283.1 medium and low expression samples. Pink arrows depict biological processes previously shown in in vitro shRNA-mediated knockdown assays. (D) ssGSEA analysis for AC009283.1 high, medium and low expression levels, depicting enrichment for cellular proliferation, cell cycle and apoptosis processes in an independent HER2-enriched breast cancer cohort.

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