Figure 4
From: Nitrate as a potential prebiotic for the oral microbiome

Effect of nitrate on oral biofilm composition at 5 h and 9 h of in vitro growth. Both Adonis and CCA p-values suggest statistically significant differences in bacterial composition on a genus-level between the control and nitrate conditions at 5 h and 9 h (for two-group comparisons, see Supplementary Figure 1). In this plot, the first constrained component clearly separates the two experimental conditions (control and nitrate), whereas the second one reflects variability due to time (5 h and 9 h), showing that both biofilm formation time and nitrate influence bacterial composition.