Table 1 Dose–response characteristics of vaginally applied agents in BLT mice.

From: Highly synergistic drug combination prevents vaginal HIV infection in humanized mice

Anti-HIV drug

EC50 (µM)

m-value, R2

TDF

4.6a

3.10, 0.977

FTC

0.56a

2.82, 0.966

VRC01-N

0.81b

4.00, 0.970

TDF-FTC-VRC01-N

N/Ac

5.62, 0.980

  1. aSee Gallay et al.27.
  2. b0.13 mg mL−1.
  3. cSee Fig. 3.
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