Table 4 Neutrophil to lymphocyte ratio (NLR) and risk of breast cancer according to total cholesterol and H2O2 levels.

From: Neutrophil to lymphocyte ratio and breast cancer risk: analysis by subtype and potential interactions

 

Total cholesterol < 193 mg/dL

Total cholesterol ≥ 193 mg/dL

Ca/Co

ORa

95% CI

ORb

95% CI

Ca/Co

ORa

95% CI

ORb

95% CI

NLR

< 1.26

18/29

1.0

 

1.0

 

38/87

1.0

 

1.0

 

1.26–1.85

22/32

1.10

0.49–2.47

0.91

0.39–2.10

75/85

1.99

1.20–3.34

1.96

1.14–3.38

> 1.85

48/48

1.59

0.78–3.32

1.41

0.66–3.04

85/62

3.01

1.80–5.10

2.79

1.60–4.91

P-trend

  

0.03

 

0.09

  

 < 0.001

 

 < 0.001

 

H2O2 < 284 ng/mL

H2O2 ≥ 284 ng/mL

Ca/Co

ORa

95% CI

ORb

95% CI

Ca/Co

ORa

95% CI

ORb

95% CI

NLR

< 1.26

9/17

1.0

 

1.0

 

9/22

1.0

 

1.0

 

1.26–1.85

28/9

5.31

1.76–17.31

5.95

1.71–23.01

20/36

1.68

0.64–4.66

1.75

0.61–5.32

> 1.85

41/21

3.65

1.38–10.22

3.30

1.12–10.40

19/36

1.53

0.58–4.24

1.74

0.59–5.43

P-trend

  

0.016

 

0.056

  

0.31

 

0.31

  1. aAdjusted for age at diagnosis (cases) and age at interview (controls).
  2. bFurther adjusted for age at menarche, parity, menopausal status, and BMI.
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