Table 1 Baseline clinical characteristics.

From: Transcriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy

Median (IQR) or N (%)

Adverse outcome (n = 23)

Good outcome (n = 22)

P value

Birth weight, g

2,730 (2,487–3,055)

2,932 (2,750–3,225)

0.03

Gestation, weeks

38 (37–40)

39 (38–40)

0.13

Gender (males)

15 (65)

11 (50)

0.35

Apgar 1 min

2 (1–3)

3 (2–3.5)

0.17

Apgar 5 min

5 (4–5)

5 (5–5)

0.10

Encephalopathy grade (moderate/severe)

14/9

20/2

0.01

Death

22 (95)

–

–

Prolonged rupture of membranes (> 24 h)

0

0

–

Maternal pyrexia

1(4)

0

0.1

Invasive Ventilation

20 (87%)

4 (18.2%)

0.0001

Perinatal sentinel events*

0

1(4)

0.3

Persistent pulmonary Hypertension

5 (21.7) (22)

0

0.03 0.02

Hypotension requiring inotropes

23 (100)

13 (59.1%)

0.001

Abnormal clotting

11 (47.8%)

3 (13.6%)

0.02

Anticonvulsants

18 (78.3%)

19 (86.4%)

0.69

  1. *Perinatal sentinel events were defined as one of the following: antepartum haemorrhage, umbilical cord mishaps, shoulder dystocia or ruptured uterus.
  2. Continuous variables were compared by using Mann–Whitney U-test and categorical variables by using Pearson chi-squared test or Fisher exact test.
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