Table 2 Acute toxicity study: effect of the mushroom extracts on kidney functioning parameters.
Parameters | 24 h Exposure | 14 day exposure | ||||
|---|---|---|---|---|---|---|
Control | Inocybe virosa extract (mg/kg bwt) | Control | Inocybe virosa extract (mg/kg bwt) | |||
250 | 500 | 250 | 500 | |||
CRE (mg/dL) | 0.27 ± 0.06 | 0.44 ± 0.06* | 0.59 ± 0.07* | 0.24 ± 0.03 | 0.31 ± 0.07 | 0.33 ± 0.06 |
BUN (mg/dL) | 23.31 ± 3.50 | 32.65 ± 2.49* | 34.59 ± 3.42* | 20.79 ± 3.68 | 23.55 ± 0.90 | 30.73 ± 3.18* |
TPR (mg/dL) | 5.03 ± 0.26 | 6.99 ± 0.13* | 7.03 ± 0.05* | 4.19 ± 0.58 | 4.98 ± 0.92 | 5.60 ± 1.45 |