Figure 1 | Scientific Reports

Figure 1

From: A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data

Figure 1

Graphical summary of the different modelling steps. (a) The core model was produced using proteomics and signaling data (obtained with a single GPCR ligand, Thrombin) obtained for human platelets and used to generate predictions regarding PI cycle driven cell signaling. (b) Mouse platelet and nucleated cell proteomic data (Cell type B) were used to populate our Core Model, generate output predictions and analyse the impact of using data from different origins in a single model.

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