Table 4 Serum levels of PIVKA-II and AFP and the serum γ-GT/ALT ratio in patients with HCC according to HBV DNA status.

From: Diagnostic value of the γ-glutamyltransferase and alanine transaminase ratio, alpha-fetoprotein, and protein induced by vitamin K absence or antagonist II in hepatitis B virus-related hepatocellular carcinoma

 

HBV DNA+/HCC (n = 110)

HBV DNA−/HCC (n = 124)

P value

PIVKA-II (mAU/mL)

7,363.10 (922.13–30,000.00)

1,883.99 (132.38–18,618.54)

0.003

AFP (ng/mL)

796.75 (76.28–20,710.95)

247.20 (14.80–5,783.58)

0.031

γ-GT/ALT

3.63 (1.64–6.05)

2.92 (1.28–5.70)

0.330

  1. Data are expressed as medians (interquartile ranges).
  2. HCC hepatocellular carcinoma, PIVKA-II protein induced by vitamin K absence or antagonist II, AFP alpha-fetoprotein, γ-GT/ALT the ratio of γ-glutamyltransferase to alanine aminotransferase.
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